The commonly used experimental animal models are transgenic mice that overexpress human genes associated with familial AD (FAD) that result in the formation of amyloid plaques.
Alzheimer's is defined by the presence and interplay of both amyloid plaques and neurofibrillary tangle pathology
Alzheimer's disease is a progressive neurologic disorder that causes the brain to shrink (atrophy) and brain cells to die.
Alzheimer's disease is the most common cause of dementia continuous decline in thinking, behavioral and social skills that has effect on person's ability to function independently.
AD -Alzheimers
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